Effect of Genetic Variants on Natural History and Treatment Response in Chronic Liver Disease

Overview

Non-Alcoholic Fatty Liver Disease (NAFLD) is expected to become the leading cause of chronic liver disease in the United States, leading to significant economic and societal burdens.  The NAFLD Biorepository aims to understand how genetic variations influence the progression and treatment outcomes of this condition, focusing on identifying genetic markers that affect the natural history of liver diseases.  By analyzing genetic, clinical, and lifestyle data from patients, researchers seek to uncover the genetic mechanisms that impact disease progression and treatment responses, ultimately developing personalized treatment strategies tailored to individuals' genetic profiles. 

Principal Investigator

Vincent Chen, MD

Digital Health Innovation Support

Digital Health Innovation provided genetic data for this project.